Peptide Blog - Omizzur

Semaglutide Intermediates Supply

Semaglutide Intermediates Supply

Semaglutide intermediate is an important raw material in the pharmaceutical industry, which is crucial for the preparation of Semaglutide API. The side chain of semaglutide contains multiple functional groups, including tert butoxide (tBuO), carboxyl (COOH), amino (NH2), and AEEA (2- [2- (Fmoc amino) ethoxy] ethoxyacetic acid) units. The presence of these functional groups endows the compound with high activity and selectivity in chemical reactions, making it suitable for various synthetic pathways.


The side chain of semaglutide is mainly used for the synthesis of semaglutide API, which is a novel hypoglycemic material. As a key raw material in the synthesis process of semaglutide, the quality and purity of the side chain directly affect the efficacy and safety of the final product.



Omizzur Popular Semaglutide Intermediates Catalog

NameCASType
Fmoc-His-Aib-OH1446013-08-6/
Boc-His(trt)-Aib-OH2061897-68-3Side chain dipeptides
Boc-His(Trt)-Aib-Glu(OtBu)-OH2750495-73-7/
Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH1890228-73-5/
Fmoc-Glu(otBu)-Gly-OH866044-63-5/
Semaglutide intermediate P291169630-82-3/
Fmoc-Arg(Pbf)-Gly-OH660846-80-0/
Fmoc-AEEA-OH166108-71-0/
HO-Ste-Glu(AEEA-AEEA-OSu)-OH1169630-40-3Semaglutide deprotection active ester modifier
Fmoc-L-Lys[Oct-(otBu)-Glu-(otBu)-AEEA-AEEA]-OH1662688-20-1Semgalutide lysine side chain
Boc-His(Trt)-Aib-Glu(OtBu)-Gly-NHS1169630-40-3Semgalutide active ester deprotection side chain
Boc-His(Trt)-Aib-Glu(OBtu)-Gly-OH1890228-73-5Semgalutide fragment tetrapeptide
C20-OtBu-Glu(OtBu)-AEEA-AEEA-OH1188328-37-1/
Fmoc-Lys(tBuO-Ste-Glu(AEEA-AEEA)-OtBu)-OH1662688-20-1Fmoc-Lys Semaglutide side chain
Ste-Glu(AEEA-AEEA-OSu)-OH1169630-40-3/
tBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu1118767-16-0Semaglutide carboxylic acid modifier
tBuO-Ste-Glu(AEEA-AEEA-OSu)-OtBu1118767-15-9Semaglutide active ester modifier
HO-Ste-Glu(AEEA-AEEA-OSu)-OH1169630-40-3Semaglutide deprotection active ester modifier
tBuO-Ste-Glu(AEEEA-AEEEA-OH)-OtBuN/ASemaglutide side chain analogue 2
Fmoc-Lys(Pal-Glu(AEEA-AEEA)-OtBu)-OHN/ASemaglutide side chain analogue 15
Ste-Glu-AEEA-AEEA-OSUN/ASemaglutide side chain OSU cleavage and disintegration
tBuO-Ste-Glu(AEEA-AEEA-ONa)-OtBuN/ASemaglutide Sodium Salt Modifier
tBuO-Ste-Glu(AEEA-AEEA-NH-pALD)-OtBuN/ASemaglutide Propionaldehyde Modified Side Chain

* For more product required please mail us: [email protected]



Research on Semaglutide


Semaglutide, a glucagon like peptide-1 (GLP-1) receptor agonist, has attracted extensive attention in the treatment of diabetes in recent years. As a weekly long-acting formulation, semaglutide effectively reduces blood sugar by simulating the action of natural GLP-1, stimulating insulin secretion and inhibiting glucagon release.


The latest research shows that semaglutide not only has excellent hypoglycemic effects, but also significantly improves cardiovascular health. In a large cardiovascular outcome trial, Semaglutide significantly reduced the risk of cardiovascular events, bringing additional cardiovascular protection to patients with diabetes.


In addition to the treatment of diabetes, the potential of Semaglutide in obesity and other metabolic diseases is also being explored. Preliminary studies have shown that semaglutide can promote weight loss and improve lipid metabolism, providing new possibilities for the treatment of these diseases.



About Omizzur Peptide


Omizzur ltd is providing +50 semaglutide intermediates & raw materials and impurities, which play a key role in the synthesis and development of semaglutide. Its unique chemical structure and excellent physical properties make this compound have broad application prospects in peptide research and production.


Semaglutide Intermediates SupplyOmizzur's main business:

Custom Peptide Synthesis

Peptide Impurities Synthesis

Fmoc/Boc/Cbz-amino acids,reagents and resins


The standardized manufacturing process of Omizzur synthetic peptides ensures that each batch of products has consistent quality and efficacy, as well as high purity characteristics, good stability, and reactivity. Omizzur strictly adheres to enterprise standards in the production process and has achieved commercial scale supply of intermediate products for semaglutide. Packaging and customized production can be carried out according to customer requirements.


Fast Link: 

√ Semaglutide Impurities Synthesis

√ Tirzepatide Intermediates

√ Tirzepatide Impurities Synthesis

√ Exenatide impurities




customer-services.jpg Order Semaglutide intermediates now:

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