Colivelin is a neuroprotective peptide with brain permeability and an effective activator of STAT3. It is a straight chain peptide composed of 26 amino acids. Colivelin inhibits neuronal death in vitro by activating STAT3; At the same time, Colivelin's neurotoxicity and A β  Sedimentation and neuronal cell apoptosis have shown long-term beneficial effects in neurodegenerative diseases. Colivelin can also be used for research related to Alzheimer's disease and ischemic brain injury.

Colivelin, as an effective synthetic derivative of human brain peptides, is a potential therapeutic compound that can restore endothelial stability and improve the prognosis of sepsis.

What is STAT3 Activator?

Signal translation and transcription activator 3 (STAT3) is a transcription factor that can activate transcriptional responses and plays an important role in various biological processes. The activation of STAT3 is mainly influenced by extracellular signals, such as cytokines and hormones. Once activated, STAT3 enters the nucleus, binds to DNA, and mediates transcriptional responses, thereby regulating gene expression.

STAT3 plays an important role in various biological effects such as immune regulation, cell proliferation, differentiation, and apoptosis. In addition, it is closely related to the occurrence and development of various diseases, including tumors, inflammatory diseases, and autoimmune diseases. The study of STAT3 helps to gain a deeper understanding of its mechanisms of action in cell biology and disease development, providing an important theoretical basis for the development of new drugs.

Colivelin TFA & Neuropeptides 

Neuropeptides are a type of long peptide chain molecules mainly distributed in the nervous system of the human body and are one of the main bodies of neural transmission. Meanwhile, due to the characteristics of neuropeptides, they also have many biological activities and therapeutic effects.

The Basic Characteristics of Neuropeptides

Neuropeptides have a complex molecular structure, high molecular weight, and are typically composed of many amino acids. They are mainly released through nerve endings and complete the transmission of neural signals by binding to receptors on the cell surface. Neuropeptides are widely distributed in the nervous system, including the brain, spinal cord, autonomic nervous system, gastrointestinal tract, and other tissues.

Neuropeptides are an important neurotrophic substance rich in protein and are the raw material for many immune active proteins in the human body. They play an important role in the immune system of the human body. At the same time, neuropeptides also have certain anti-tumor activity and can play an auxiliary role in the treatment of certain tumor diseases. Neuropeptides have been used in the treatment of diseases such as Alzheimer's, concussion, and Parkinson's disease.

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Colivelin TFA | CAS 867021-83-8 | Omizzur Peptide

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-20 ℃, dry, it is not recommended to store in solution state.

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