Liraglutide Impurities Synthesis

Liraglutide is a long-acting GLP-1 analog, which is currently widely used in the treatment of type 2 diabetes. Liraglutide is formed by adding a 16 carbon palmitoyl fatty acid at position 26 of GLP-1 through gene recombination technology, and replacing lysine at position 34 of GLP-1 with arginine; These structural modifications increase aggregation and promote the binding of non covalent albumin, so the half-life of lalutide is much longer than that of GLP-1.

Related substances of synthetic peptides are mainly: process impurities brought into the synthesis process, such as missing peptides, broken peptides, oxidized peptides and other peptide related substance; Degradation products and polymers produced by peptide deamidation, oxidation, hydrolysis, disulfide bond mismatch, racemization and other unstable factors.. For some synthetic peptide drugs, the impurity content is high, and when the activity or safety is not clear, in-depth research should be carried out to control the impurity level within a reasonable range. Omizzur custom synthesized various peptide related impurities.

It is valid for at least one year if stored at -20 ℃ or lower. Since each freezing and thawing of polypeptide will cause partial inactivation, after the storage solution with corresponding concentration is prepared for the first time (please prepare the storage solution according to the information in the column of reconstitution in the product introduction), it must be frozen at -20 ℃ or lower after sub packaging to avoid repeated freezing and thawing.

Shipping: By air or FedEx Express, delivery time: 5-10 days

Matters Needing Attention:

This product is freeze-dried powder. Since a small amount of polypeptide is deposited in the tube during the freeze-drying process, forming a very thin or invisible polypeptide layer, before opening the tube cover, we recommend centrifuging about 8000-12000g in a centrifuge for 10-30 seconds to make the polypeptide attached to the tube cover or tube wall gather at the bottom of the tube.

This product is only used for scientific research by professionals, and shall not be used for clinical diagnosis or treatment, food or drugs, or stored in ordinary houses.

For your safety and health, please wear lab clothes and disposable gloves.

Quality Assurance

1. For all batches of products, we will keep samples after one year of validity. When customers raise objections, we can make a quick response.

2. For the products purchased by customers, an original of our inspection report will be attached with the goods, including batch number, date, etc.

3. If you have any problems in use, please feel free to contact us and we will help you solve them as soon as possible.

Order Guidance

1. After you confirm the purchase, please inform our sales staff of your detailed requirements, including product name, quantity, packaging requirements, etc., as well as your receiving address, company name and contact information; Then our sales staff will make an order for you.  

2. Omizzur is a professional peptide manufacturer, there will be a huge discounts for bulk purchase. Distributors are welcomed.