This article will introduce Omizzur biotech’s peptide CDMO services and its main advantageous peptide products. The article is about 1,300 words and takes 2.5 minutes to read.

What are peptides? A Unique Molecule!

Peptides can be thought of as "smaller proteins." Peptides are a type of compound formed by connecting multiple amino acids through peptide bonds. They are usually composed of 10 to 100 amino acids. They are connected in the same way as proteins and have a molecular weight of less than 10,000.

Although peptides and proteins are linear molecules formed by linked amino acids. Natural proteins and complex peptide usually have unique space structures. Peptide drugs are specific applications of peptides in the medical field. It has the characteristics of high activity, low dose and low toxicity.

The molecular size of peptide drugs is between small molecule chemical drugs and large molecule protein drugs. Compared with small molecule drugs, peptide drugs have higher activity and stronger selectivity. Compared with protein drugs, peptide drugs have the advantages of low immunogenicity, high purity, and low production cost. 

But at the same time, peptide drugs also have two disadvantages: low membrane permeability and poor stability in vivo. Scientists have improved these 2 problems in a variety of different ways.

Omizzur biotech is a leading CDMO company which provides custom peptide services for pharmaceutical companies worldwide. Omizzur has great advantages in the fields of popular pharma-grade peptides, research-grade peptides and protected amino acids.

Omizzur Ltd CDMO Services

■ Contract research for API production                                                      ■ Contract research for formulation 

■ Synthesis and production services for peptide APIs                              ■ Marketing license holder (MAH)                        

Why choose Omizzur Ltd?

1. Leading R&D and production capabilities:

Omizzur is currently involved in 35 cGMP projects for new chemical entities (all innovative drugs). Omizzur's inventory can supply 1,000 peptides and related reagents, and it also has large-scale production for peptides from gram level to hundreds of kilograms per year.

2. Omizzur ltd provides pharma companies and R&D institutions with CDMO services such as small trials, pilot trials, process research and development, and customized production of peptide drugs. We have rich experience in the field of peptide drugs.

3. Complete synthesis and purification system.

In terms of peptide technology, Omizzur ltd masters a variety of tech methods including solid, liquid phase synthesis, solution reaction synthesis, etc. Secondly, Omizzur ltd also has complete peptide purification and analysis technology, as well as preparation tech for a variety of APIs.

4. Covers a variety of peptide APIs/advanced pharma intermediates.

The Omizzur CDMO product line includes well-known varieties such as semaglutide, and liraglutide etc. It is one of the companies on the market capable of large-scale production of kilogram-level semaglutide API. The company has 4 GMP raw material workshops with an annual production capacity of 200kg freeze-dried powder.

5. Rich project experience

Omizzur ltd APIs have reached 40 countries and regions around the world, providing APIs for 8 commercial projects and more than 100 clinical projects around the world. Omizzur ltd's commercial CDMO projects are mainly distributed in the United States, India, and Europe.

Peptide API & Impurities                               Research-level Peptide

√  Exenatide                                                                             √  RGD peptide

√  Semaglutide                                                                        √  Amyloid peptide

√  Salmon calcitonin                                                                √  Melittin

The chemical synthesis method has the advantages of short development cycle and rapid production. It can be divided into liquid phase and solid phase method. The main difference between the two comes from whether a solid phase carrier is used. Liquid-phase synthesis developed earlier, and solid-phase synthesis is now the main method for peptide synthesis.

Basic Principles of Solid Phase Synthesis:

1) First, connect the carboxyl group of the C-terminal amino acid of the target peptide chain to be synthesized to an insoluble polymer resin in the form of a covalent bond.

2) Using the amino group of the amino acid as the starting point, connect the deprotected N-terminus of the amino acid to the second amino acid whose carboxyl group has been activated through a condensation.

3) Repeat the condensation → washing → deprotection → neutralization and washing → next round of condensation to reach the length of the peptide chain to be synthesized. followed by peptide cutting, modification, separation and purification, finally will obtain the target peptide.

The solid-phase method is suitable for the synthesis of 10-50 amino acids. According to different α-amino protecting groups, solid-phase synthesis methods can be divided into Boc method and Fmoc method. The solid-phase method is easy to operate, it is easy to automate repeated operations, and the product yield and purity are high. It greatly promotes the R&D of peptide drugs.

Customer Service Center

 Research Peptides Order: 

 1. Inquiry Online 

 2. Mail us now: [email protected]

  * Please mail us your product name and quantity needed, Omizzur customer services will get in touch with you within 1 hour.