Fmoc-His-Aib-OH.TFA

Omizzur > Peptide Products > Amino Acids and Resins > Fmoc amino acids > Fmoc-His-Aib-OH.TFA

* For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Name	Fmoc-His-Aib-OH.TFA
CAS	1446013-08-6
Purity % (HPLC)	> 98.0% (HPLC)
Pack size	CIF Price ( USD )	Inventory
10 g	$150.0	In stock
1000 g	Please inquire the lowest	In stock

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General Description Product Data Sheet Shipping & Storage Ordering Guide

General Description

Fmoc-His-Aib-OH.TFA

Fmoc-His-Aib-OH.TFA | Omizzur Fast Shipping

Fmoc-His-Aib-OH.TFA is an amino acid derivative that can be used for the synthesis of semaglutide. In addition, Fmoc-His-Aib-OH.TFA is a side chain dipeptide of semaglutide, and the N-terminus of the peptide is blocked by an fmoc group to enhance its stability.

Fmoc-His-Aib-OH.TFA is an important intermediate in the chemical synthesis of semaglutide dipeptides.

The side chain of semaglutide is mainly used for synthesizing the hypoglycemic drug semaglutide. Semaglutide is a long-acting GLP-1 receptor agonist, which is a powerful and durable anti diabetes drug for subcutaneous injection. Semaglutide was approved for market by the US Food and Drug Administration (FDA) in December 2017, becoming the seventh drug of its kind approved globally after several other GLP-1RA drugs.

Semaglutide improves its therapeutic efficacy by altering the sequence structure of endogenous GLP-1 and modifying the fatty acid side chains on the peptide backbone to bind with human albumin, thereby prolonging the plasma half-life.

Other Hot Semaglutide Intermediates:

Intermediate of Semaglutide	Sequences	CAS
Semaglutide lysine side chain	Fmoc-L-Lys[Oct-(otBu)-Glu-(otBu)-AEEA-AEEA]-OH	1662688-20-1
Deprotection of side chains of active ester of Semaglutide	Boc-His(Trt)-Aib-Glu(OtBu)-Gly-NHS	1169630-40-3
Semaglutide dipeptide modifier	Boc-His(Trt)-Aib-OH	2061897-68-3
Semaglutide fragment tetrapeptide	Boc-His(Trt)-Aib-Glu(OBtu)-Gly-OH	1890228-73-5

Application Prospects of Intermediate of Semaglutide

As a novel insulin replacement drug, the side chain structure of semaglutide has a significant impact on its pharmacological effects. By appropriately modifying the side chain of semaglutide, its biological activity and stability can be further enhanced, providing a better choice for the prevention and treatment of metabolic diseases. Therefore, the research and development of the side chain of semaglutide have important scientific significance and clinical application value.

Product Data Sheet

Fmoc-His-Aib-OH.TFA Spot Supply

Name	Fmoc-His-Aib-OH.TFA
CAS	1446013-07-5 No TFA / 1446013-08-6 TFA
Type	Semaglutide Intermediates
IUPAC	N-(fluorenylmethoxycarbonyl)-L-histidyl-alpha-methyl-alanine
Purity (HPLC)	98.0% min
Source	Synthetic
Molecular Formula	C25H26N4O5.C2HF3O2
Molecular Weight	576.53
Package	10g, 100g, 500g, 1kg, 10kg or according to customer's detail requirement.
Inventory	In stock

Shipping & Storage

Fmoc-His-Aib-OH Notice:

The storage conditions for the side chain of semaglutide (Fmoc-His-Aib-OH) are usually -20 ° C and require an inert gas environment to ensure its stability and activity. When using the side chain of semaglutide for drug synthesis, relevant operating procedures and safety standards should be strictly followed to ensure the safety and effectiveness of the production process.

Storage: -20°C, avoid light, cool and dry place.

Shipping: Ship by FedEx door to door / DHL / By air.

Ordering Guide:

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