Fmoc-Glu(OtBu)-Gly-OH | Semaglutide Fragment In Stock 

Fmoc-Glu(OtBu)-Gly-OH (CAS 866044-63-5) is a small peptide fragment composed of two amino acids, with the amino end of the peptide properly sealed. It is commonly used in the synthesis of semaglutide or other peptides.

The Synthesis Process of Semaglutide:

The synthesis process of semaglutide first requires the selection of suitable raw materials, which are crucial for the success of the synthesis process. The synthesis of semaglutide mainly uses solid-phase peptide synthesis technology, and the most commonly used raw materials are the fmoc/boc amino acids used to synthesize peptide chains. These amino acids are connected together through chemical reactions in order and method to form the structure of the peptide chain.

The synthesis mainly includes the following steps: protecting group removal, activation, coupling, and protecting amino acids. Protecting group removal is the process of removing the protecting group of an amino acid so that it can be linked to other amino acids. Activation is the process of reacting an amino acid with an active agent so that it can react with other amino acids in the coupling reaction. Coupling is the process of linking an activated amino acid to another amino acid to form the structure of a peptide chain. These steps are then repeated to synthesize the complete semaglutide.

Fmoc-Glu(OtBu)-Gly-OH is a key raw material for the synthesis of semaglutide, Omizzur provides a large supply of the following semaglutide fragments and related impurities in stock:

Precautions for Synthesizing Semaglutide

In the synthesis process of semaglutide, it is necessary to ensure the efficiency of each reaction step. In order to improve the efficiency of the reaction, catalysts or specific reaction conditions can be used to accelerate the reaction rate and increase the yield. To ensure the selectivity of the reaction, protective techniques can be used.

During the synthesis process, it is necessary to optimize factors such as reaction conditions, temperature control, and reaction time, which will directly affect the effectiveness and yield of the reaction. Therefore, a large number of experiments are needed to determine the optimal synthesis conditions.

In addition, the synthesis process also requires analysis and purification of reactants and products. Analysis can determine the structure and purity of compounds through techniques such as mass spectrometry and infrared spectroscopy. Purification can use techniques such as counter current chromatography to separate and purify products. A large number of experiments are required during the synthesis process to ensure the effectiveness and yield of the synthesis, and these synthesis processes need to be continuously improved and perfected.

Omizzur Biotech

Omizzur is a company specializing in the production of amino acid derivatives, currently offering a wide range of fmoc/boc-amino acids, unnatural amino acids, various peptide reagents, and resins. The total number of products exceeds 1000.

Omiizzur provides comprehensive product quality analysis reports (HPLC, MS, COA), the products are not limited to the above varieties. Please contact our customer services for product catalogs, delivery date, and quotations.

Fmoc-Glu(OtBu)-Gly-OH Spot Supply

Storage: Cool dry place( Store at -20°C, away from the light)

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