Fmoc-Arg(Pbf)-Gly-OH-660846-80-0
| Name | Fmoc-Arg(Pbf)-Gly-OH | |
| CAS | 660846-80-0 | |
| Purity % (HPLC) | > 99.0% (HPLC) | |
| Pack size | CIF Price ( USD ) | Inventory |
| 25g | $500.0 | In stock |
| 1000g | Make Inquiry | In stock |
Omizzur Biotech Online Inquiry Form
Notice:
1.Omizzur follows strict guidelines on the use of private information.
2.For bulk inquiry or custom packaging: [email protected]
3.Our customer service staff will contact you in 1 hour. Please check your email
General Description
Fmoc-Arg(Pbf)-Gly-OH is commonly used in solid-phase synthesis (SPPS) for the synthesis of peptide chains or proteins, such as the Semaglutide API.
Currently, popular research products on semaglutide include semaglutide fragments, semaglutide side chains, semaglutide impurities and APIs. Omizzur provides some Semaglutide products in stock, while others require customization.
Popular Semaglutide Fragments - Omizzur
| Name | CAS | Type |
| Fmoc-His-Aib-OH | 1446013-08-6 | Semaglutide side chain dipeptide |
| Boc-His(trt)-Aib-OH | 2061897-68-3 | Semaglutide side chain dipeptide |
| Boc-His(Trt)-Aib-Glu(OtBu)-OH | 2750495-73-7 | N/A |
| Fmoc-AEEA-OH | 166108-71-0 | N/A |
| Boc-His(Trt)-Aib-Glu(OtBu)-Gly-NHS | 1169630-40-3 | Deprotection of side chains of active ester of Semgalutide |
| HO-Ste-Glu(AEEA-AEEA-OSu)-OH | 1169630-40-3 | Semaglutide deprotection active ester modifier |
Solid Phase Synthesis of Peptides
At present, the most effective chemical synthesis method for peptide drugs is solid-phase synthesis, which starts from the carboxyl end of the peptide, connects the first amino acid to the resin, removes the protective group of the amino acid, couples the next amino acid according to the peptide sequence, removes the amino protective group, and then couples again, repeating the process until the amino acid assembly is completed.
By cleaving the peptide from the resin and removing all protective groups, crude peptide can be obtained, which is then purified and freeze-dried to obtain peptide active pharmaceutical ingredients (APIs).
The Synthesis of Semaglutide is Challenging
The conventional solid-phase synthesis method of semaglutide presents great challenges, mainly manifested in the presence of a large number of hydrophobic amino acids on the main chain, which stabilizes the hydrogen bonds between peptide chains and can result in severe folding; The increased interaction between peptide chains leads to resin shrinkage and increases the difficulty of amino acid coupling; Reduced reaction activity and efficiency of coupling, decreased reaction yield, and increased cost.
Product Data Sheet
| Name | Fmoc-Arg(Pbf)-Gly-OH |
| CAS | 660846-80-0 |
| Alias | (9H-Fluoren-9-yl)MethOxy]Carbonyl Arg(Pbf)-Gly-OH |
Type | Key starting materials for semaglutide; Pharmaceutical intermediates |
| Purity (HPLC) | 98.0% min |
| Source | Synthetic |
| Molecular Formula | C36H43N5O8S |
| Molecular Weight | 705.82 |
| Appearance | White or off white solid powder |
| Package | 10g, 25g,100g, 500g, 1kg, or according to customer's requirement. |
| Inventory | In stock |
Shipping & Storage
Storage: Fmoc-Arg(Pbf)-Gly-OH should be stored in a cool and dry place, away from sources of fire and high temperatures.
Shipping: Fast delivery by FedEx, DHL, By air.
Ordering Guide:
Quote & Order of Fmoc-Arg(Pbf)-Gly-OH:
1. Click to send inqauiry online: Make Inquiry Now
2. Send mail to us: [email protected]
* Please mail us your product name and quantity needed, Omizzur services will get back to you within 1 hour.
Customer also viewed
Fmoc-AEEA-OH
CAS:166108-71-0
Fmoc-Glu(OtBu)-Gly-OH
CAS:866044-63-5
Boc-His(Trt)-Aib-OH
CAS:2061897-68-3
Fmoc-His-Aib-OH.TFA
CAS:1446013-08-6
Enquiry & Ordering Form
Method 1
Simply email to [email protected] ,you will get a fast response within 1 hour.
Method 2
Submit the simple form to get the latest quotation. Notice:Omizzur follows strict guidelines on the use of private information.
Copyright © 2020 Omizzur Inc | Terms & Conditions | Privacy Notice | Sitemap
