Fmoc-AEEA-OH
Name | Fmoc-AEEA-OH | |
CAS | 166108-71-0 | |
Purity % (HPLC) | > 99.0% (HPLC) | |
Pack size | CIF Price ( USD ) | Inventory |
25g | $600.0 | In stock |
1000g | Make Inquiry | In stock |
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General Description
Fmoc-AEEA-OH is a key intermediate for the synthesis of Semaglutide (a therapeutic drug for diabetes), and a compound of Elabote(an anti AIDS drug). This modified PEG and its homologues can also be used in drug research and development, such as modifying protein drugs, peptide compounds, liposomes, and small molecule drugs through coupling reactions.
Fmoc-AEEA-OH is an organic synthesis intermediate and pharmaceutical intermediate that can be used in laboratory research and chemical pharmaceutical synthesis processes.
Fmoc-AEEA-OH application: One of the key starting materials for semaglutide API. Omizzur is supplying a large quantity of Fmoc-AEEA-OH worldwide.
Popular Semaglutide Raw Materials & Intermediates
Semaglutide Fragment & Intermediates | CAS | |
1 | Fmoc-His-Aib-OH.TFA | 1446013-08-6 |
2 | Boc-His(trt)-Aib-OH | 2061897-68-3 |
3 | Fmoc-Glu(otBu)-Gly-OH | 866044-63-5 |
4 | Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH | 1890228-73-5 |
5 | Fmoc-Arg(Pbf)-Gly-OH | 660846-80-0 |
6 | HO-Ste-Glu(AEEA-AEEA-OSu)-OH | 1169630-40-3 |
7 | Ste-Glu(AEEA-AEEA-OSu)-OH | 1169630-40-3 |
8 | Fmoc-AEEA-OH | 166108-71-0 |
9 | HO-Ste-Glu(AEEA-AEEA-OSu)-OH | 1169630-40-3 |
*** Omizzur amino acid derivative products are not limited to the above varieties. If you have any other amino acid requirements, please contact our customer services.
The Synthesis Problem of Semaglutide & Solution
The existing synthesis process of semaglutide also includes some traditional peptide solid-phase synthesis and fragment condensation synthesis methods. Among all these various methods, it is basically difficult to achieve good synthesis results using linear coupling. Mainly due to the peptide sequence structure of semaglutide itself, the N-terminal fragment is prone to form secondary structures such as β - folding due to its strong hydrophobicity, making coupling very difficult and the condensation efficiency very low.
Some methods of fragment condensation are also aimed at solving the problem of difficult linear coupling. However, some current methods of fragment condensation, when the synthesis scale is scaled up to production, issues such as fragment dissolution, coupling efficiency, and exothermic dissolution can all affect the final synthesis effect. In addition, fragment condensation is also relatively complex in operation, which is not conducive to industrial production.
Omizzur Biotech overcomes the problem of condensation and provides Semaglutide API, Semalutide intermediates and Impurities, fmoc-amino acids ( for example Fmoc-AEEA-OH), etc. for scientific research institutions and pharmaceutical companies to use.
About Omizzur Biotech
Omizzur is engaged in the production and research and development of various peptide raw materials and intermediates, such as Fmoc/boc amino acids, unnatural amino acids, peptide reagents, and resins. We also provide custom peptide synthesis and impurities for scientific research experiments. Please contact Omizzur customer services for the latest product catalog.
Product Data Sheet
Name | Fmoc-AEEA-OH |
CAS | 166108-71-0 |
Alias | Fmoc-8-amino-3,6-dioxaoctanoic acid |
Type | Key starting materials for semaglutide; Pharmaceutical intermediates |
Purity (HPLC) | 99.0% min |
Source | Synthetic |
Molecular Formula | C21H23NO6 |
Molecular Weight | 385.41 |
Boiling point | 631.4±45.0 °C(Predicted) |
Appearance | White crystalline powder |
Solubility | Soluble in chloroform, DMSO, methanol (small amount) |
Package | 10g, 25g,100g, 500g, 1kg, or according to customer's requirement. |
Inventory | In stock |
Shipping & Storage
Storage: Cool dry place(≤8°C)
Shipping: Global fast delivery: via FedEx, DHL, air freight.
Ordering Guide:
Quote & Order of Fmoc-AEEA-OH:
1. Click to send inqauiry online: Make Inquiry Now
2. Send mail to us: [email protected]
* Please mail us your product name and quantity needed, Omizzur services will get back to you within 1 hour.
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Enquiry & Ordering Form
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